Abstract
Introduction (with objective): The Specialized Component of Pharmaceutical Assistance (CEAF) plays a central role in the Unified Health System (SUS) by ensuring access to medications for chronic and more complex conditions. Analysis of dispensing patterns allows for the identification of priority demands and supports the organization of services, in accordance with Clinical Protocols and Therapeutic Guidelines (PCDT), currently totaling 98 protocols. This study aimed to analyze the most dispensed medications in the CEAF of Paraíba in 2025, relating them to the volume of care and the main lines of care. Material and Method: This is a descriptive, quantitative study based on secondary data from official pharmaceutical assistance systems. Results: 84,441 users were served up to December 2025, with 2,930,840 services provided up to November (an average of 34.7 services/user/year) and 42,261 telephone calls, highlighting a high demand for care. The ranking of the most dispensed medications was led by formoterol + budesonide (4,821,451 units; 26.6%), followed by dapagliflozin (3,159,761 units; 17.4%) and sevelamer (2,262,229 units; 12.5%). Together, the top three accounted for 56.5% of the volume among the ten most dispensed. Following this, the most prominent medications are olanzapine (9.0%), calcitriol (7.7%), gabapentin 400 mg (6.9%), gabapentin 300 mg (5.5%), tacrolimus (5.3%), quetiapine (4.7%), and clozapine (4.4%), totaling 18,137,139 pharmacological units. The medications are concentrated in care pathways related to chronic diseases with high prevalence and clinical impact, such as respiratory diseases, diabetes, chronic kidney disease, mental disorders, and post-transplant conditions, highlighting the predominance of continuous therapies. The high ratio of consultations to users, associated with the volume dispensed, indicates intensive longitudinal demand and reinforces the role of the CEAF (Center for Pharmaceutical Assistance) in guaranteeing access. On the other hand, it highlights challenges related to operational capacity, organization of flows, and quality of care, especially regarding pharmacotherapeutic follow-up, adherence to PCDTs (Clinical Protocols and Therapeutic Guidelines), and integration between levels of care. Conclusions: It is concluded that the dispensing profile at the CEAF in Paraíba in 2025 is strongly driven by chronic diseases, with a high concentration among the most used medications, highlighting the centrality of pharmaceutical care in the organization of care and the rational use of medicines in the SUS (Brazilian Public Health System).
