Padrões de tratamento e alcance de metas terapêuticas em uma coorte de pacientes com diabetes mellitus tipo 2 tratados no sistema de saúde privado brasileiro (PHCS) – relatórios iniciais do estudo diaps 79
Padrões de tratamento e alcance de metas terapêuticas em uma coorte de pacientes com diabetes mellitus tipo 2 tratados no sistema de saúde privado brasileiro (PHCS) - relatórios iniciais do estudo diaps 79
Tipo de documento
Apresentação
Descrição
Resumo apresentado na The Professional Society for Health Economics and Outcomes Research (ISPOR)
Fonte
ISPOR
Ano de publicação
2010
Referência (Vancouver)
DIAPS79 study group, Eliaschewitz FG, Bahia L, Cintra M, Franco L, Nita ME, Rached R. Treatment patterns and achievement of therapeutic goals in a cohort of type 2 diabetes mellitus patients treated in the Brazilian private health care system (PHCS)- initial reports of diaps 79 study [Internet]. In: ISPOR Europe 2010; Prague, Czech Republic. Disponível em: https\://www\.ispor.org/heor-resources/presentations-database/presentation/ispor-13th-annual-european-congress/treatment-patterns-and-achievement-of-therapeutic-goals-in-a-cohort-of-type-2-diabetes-mellitus-patients-treated-in-the-brazilian-private-health-care-system-phcs-initial-reports-of-diaps-79-study
Treatment Patterns and Achievement of Therapeutic Goals in a Cohort of Type 2 Diabetes Mellitus Patients Treated in the Brazilian Private Health Care System (PHCS)- Initial Reports of Diaps 79 Study.
Document type
Presentation
Description
Abstract presented at The Professional Society for Health Economics and Outcomes Research (ISPOR)
Source
ISPOR
Publication year
2010
Reference (Vancouver)
DIAPS79 study group, Eliaschewitz FG, Bahia L, Cintra M, Franco L, Nita ME, Rached R. Treatment patterns and achievement of therapeutic goals in a cohort of type 2 diabetes mellitus patients treated in the Brazilian private health care system (PHCS)- initial reports of diaps 79 study [Internet]. In: ISPOR Europe 2010; Prague, Czech Republic. Available from: https\://www\.ispor.org/heor-resources/presentations-database/presentation/ispor-13th-annual-european-congress/treatment-patterns-and-achievement-of-therapeutic-goals-in-a-cohort-of-type-2-diabetes-mellitus-patients-treated-in-the-brazilian-private-health-care-system-phcs-initial-reports-of-diaps-79-study
Objetivos: Investigar as práticas de tratamento para diabetes tipo 2 (T2DM) e o alcance das metas terapêuticas entre pacientes com T2DM tratados no Sistema de Saúde Privado (PHCS) Brasileiro. Métodos: Esta análise transversal envolveu 383 pacientes ambulatoriais com T2DM de 5 cidades dentro do PHCS. Os dados foram coletados do ano anterior através de entrevistas com pacientes usando um questionário validado e revisão de prontuários médicos. As metas terapêuticas foram baseadas nas recomendações da Sociedade Brasileira de Diabetes. Resultados: - Características dos Pacientes: - Idade média: 60,5±9,6 anos - IMC médio: 29,1±5,3 kg/m² - Duração média do diabetes: 12,2±8,75 anos - Comorbidades: - Hipertensão arterial: 66,8% (n=256) - Obesidade: 39% (n=144) - Dislipidemia: 69,6% (n=267) - Insuficiência cardíaca: 5,5% (n=21) - Complicações: - Complicações microvasculares: 32,4% (n=124) - Complicações macrovasculares: 8,1% (n=31) - Complicações micro e macrovasculares: 18% (n=69) - Sem complicações: 41,5% (n=159) - Práticas de Tratamento Atuais: - Somente dieta: 3,6% (n=14) - Monoterapia com medicamentos antidiabéticos orais (OAD): 30% (n=115) - Terapia combinada com múltiplos OADs: 37,8% (n=145) - Terapia combinada com insulina: 23,2% (n=89) - Somente insulina: 5,2% (n=20) - Medicamentos mais prescritos: Metformina (41,4%), Insulina (19,1%), Sulfonilureias (18,6%), Inibidores de DPP4 (8,7%), TZDs (5,5%) e outros (6,7%) - Medicamentos para dislipidemia: 47,5% (n=178) - Medicamentos cardiovasculares: 77,4% (n=287) - Medicamentos anti-obesidade: 4% (n=15) - Alcance das Metas de Tratamento: - Pressão arterial sistólica e diastólica (<130x85 mmHg): 76,8% - IMC 55 mg/dL (mulheres): 28% - Colesterol HDL >45 mg/dL (homens): 37,3% - HbA1c dentro da faixa normal: 28,2% - Todas as metas de tratamento alcançadas: 6,8% (n=26) Conclusões: Na prática clínica real, as metas nacionais para controle glicêmico, pressão arterial e níveis lipídicos raramente são alcançadas, apesar do alto uso de medicamentos.
Notas
O registro foi originalmente publicado em inglês. A versão em português foi traduzida com o apoio de inteligência artificial.
Abstract
Objetives: Investigate the type 2 diabetes mellitus (T2DM) treatment practice and achievement of therapeutic goals in a cohort of T2DM patients treated in the Brazilian PHCS. Methods: This is a cross-sectional analysis of 383 T2DM outpatients treated in 5 cities covered by the PHCS. Data was collected using information from the previous year by interviewing patients using a validated questionnaire complemented by medical chart review. Therapeutic goals suggested by the Brazilian Diabetes Society were used as standard treatment. Results: Mean age was 60.5±9.6 years, mean BMI 29.1±5.3 Kg/m2 and mean duration of diabetes of 12.2±8.75 years. The frequency of associated arterial hypertension was 66.8% (n=256); obesity 39% n=144); dyslipidemia 69.6% (n=267) and heart failure 5.5% (n=21). Microvascular complications were present in 32.4% (n=124); 8.1% (n=31) had macrovascular complications; 18% (n=69) had at least one micro and one macrovascular complication and 41.5% (n=159) had no complications. Current treatment practice was: 3.6% (n=14) diet only; 30% (n=115) monotherapy with oral anti-diabetic (OAD); 37.8% (n=145) combined therapy with more than one OAD agents; 23.2% (n=89) combined therapy with insulin and 5.2% (n=20) just insulin. The most prescribed drug was metformin (41.4%), followed by insulin (19.1%), sulphonylureas (18.6%), DPP4 inhibitors (8.7%), TZDs (5.5%), and others (6.7%). Medications for dyslipidemia was used by 47.5% (n= 178); cardiovascular drugs in 77.4% (n=287) and anti-obesity drugs in 4% (n=15). Treatment targets were achieved in: 76.8% for systolic and diastolic blood pressure (<130x85 mmHg), 19.5% for BMI 55 women, 37.3% for HDL cholesterol >45 men and 28.2% reached the goal for HbA1c (within normal range). Only 6.8% of the group (n=26) reached all the treatment targets. Conclusions: The national goals for glycemic control, blood pressure and lipid levels are rarely achieved in real-world clinical practice, even with the high use of medications.
Notes
The record was originally published in English. The Portuguese version was translated with the aid of artificial intelligence.
