Abstract
Introduction: The concomitant use of allopathic and herbal medicines is common among the population, often without proper professional monitoring. The role of the pharmacist in this context is essential to ensure the rational and safe use of these combined therapies. Phytotherapy, when properly guided, can complement conventional pharmacological treatment, but it can also result in undesirable interactions and side effects. Thus, the critical and individualized analysis of the practices involving the use of medicinal plants, as well as the identification of drug interactions, is essential for a safe and effective therapeutic approach. Objective: To analyze possible interactions between medications and medicinal plants used by a patient, through an extension course, in order to promote the rational and safe use of phytotherapy, carrying out an evidencebased pharmaceutical prescription. Methods: This is a qualitative, clinical, and interventional study conducted through inperson meetings with a patient. Initially, a structured pharmaceutical anamnesis was conducted, including sociodemographic data, health history, use of prescription and nonprescription medications, and medicinal plants. Based on this information, a pharmacotherapeutic diagnosis was developed, identifying possible drug interactions. Based on the reported complaints and scientific evidence, a pharmaceutical prescription of herbal medicines was made. Subsequently, feedback was provided, along with the delivery of a personalized booklet containing therapeutic guidance. After a period of use, a new consultation was conducted to clinically assess the effects of the intervention and the need for adjustments to the therapeutic plan. Results: Interactions were observed between the patient's ongoing medications, such as levothyroxine, naratriptan, scopolamine, and rosuvastatin + ezetimibe, and some medicinal plants used, namely Melissa officinalis and Matricaria recutita (chamomile). After analysis of scientific databases to verify possible interactions with the medications used by the patient, the use of Passiflora incarnata (passion fruit), with anxiolytic, sedative, and calming effects, and Hibiscus sabdariffa (hibiscus), with antioxidant, diuretic, and lipidlowering properties, was recommended instead of the medicinal plants previously used by the patient. The patient was receptive to the recommendations and reported subjective improvements, especially related to the use of hibiscus. The guidance to avoid the use of lemon balm due to its potential interaction with thyroid hormones was also followed. Pharmaceutical followup demonstrated the importance of continuous and individualized care. Conclusion: The study highlights the importance of pharmaceutical practice in identifying drug interactions and prescribing herbal medicines based on the individual needs of the patient. The extensionbased approach, through guided and educational consultations, provided the patient with a greater understanding of the appropriate use of medicinal plants and medications. It is concluded that the integration of scientific knowledge and clinical practice is essential to promote the safe and effective use of phytotherapy, reinforcing the role of the pharmacist as a healthpromoting agent.
